Movers and SHAKERS
Number of Patients with a Complete Response Increases in AML Study
Trovagene, Inc. is a clinical stage biotechnology company focused on the development of new therapeutics for hematology and oncology. The company's clinical programs of Onvansertib (PLK1 inhibitor) include Phase 1b/2 study in AML, Phase 1b/2 study in mCRPC and Phase 1b/2 trial in KRAS-mutant colorectal cancer.
Ahu Demir, Ph.D., Biotechnology Research Analyst, Noble Capital Markets, Inc.
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- AML study update at ESMO. Trovagene presented updated data from the Phase 1b/2 study assessing Onvansertib in combination with standard-of-care chemotherapy (low-dose cytarabine (LDAC) or decitabine) in acute myeloid leukemia (AML). Four patients among 24 achieved objective responses, two with complete remission (CR) and two with incomplete hematologic recovery (iCR).
- Higher doses of Onvansertib are more effective. The patients who were treated with the highest two doses (27, 40 mg/m2) of Onvansertib demonstrated...
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